John Sundy, MD, PhD

Department:
Medicine

Division:
Rheumatology and Immunology

Physical Address:
DUMC 3278, Durham, NC 27710

Appointment Telephone:
(919) 668-2169

Fax Telephone:
(919) 681-8298

Training:
M.D., Hahnemann University, Pennsylvania, 1991
Internal Medicine, Duke University Medical Center, North Carolina, 1991-93
Rheumatology, Duke University Medical Center, North Carolina, 1993-95
Allergy and Immunology, Duke University Medical Center, North Carolina, 1995-96
Ph.D., Immunology, Hahnemann University, Pennsylvania, 1991

Clinical Interests:
Gout, autoimmunity

Publications:
2008 -- Pubmed # 18472151 -- Hauswirth DW, Sundy JS, Mervin-Blake S, Fernandez CA, Patch KB, Alexander KM, Allgood S, McNair PD, Levesque MC. Normative values for exhaled breath condensate pH and its relationship to exhaled nitric oxide in healthy African Americans. J Allergy Clin Immunol. 2008 Jul;122(1):101-6.

2008 -- Pubmed # 18036642 -- Levesque MC, Hauswirth DW, Mervin-Blake S, Fernandez CA, Patch KB, Alexander KM, Allgood S, McNair PD, Allen AS, Sundy JS. Determinants of exhaled nitric oxide levels in healthy, nonsmoking African American adults. J Allergy Clin Immunol. 2008 Feb;121(2):396-402.e3.

2008 -- Pubmed # 18759308 -- Sundy JS, Becker MA, Baraf HS, Barkhuizen A, Moreland LW, Huang W, Waltrip RW 2nd, Maroli AN, Horowitz Z, . Reduction of plasma urate levels following treatment with multiple doses of pegloticase (polyethylene glycol-conjugated uricase) in patients with treatment-failure gout: Results of a phase II randomized study. Arthritis Rheum. 2008 Sep;58(9):2882-91.

2008 -- Pubmed # 18975368 -- Sundy JS. Gout management: let's get it right this time. Arthritis Rheum. 2008 Nov 15;59(11):1535-7.

2007 -- American Lung Association Asthma Clinical Research Centers (including JS Sundy). 2007. Clinical trial of low-dose theophylline and montelukast in patients with poorly controlled asthma. Am J Respir Crit Care Med 175(3): 235-42.

2007 -- Pubmed # 17328081 -- Sundy JS, Ganson NJ, Kelly SJ, Scarlett EL, Rehrig CD, Huang W, Hershfield MS. Pharmacokinetics and pharmacodynamics of intravenous PEGylated recombinant mammalian urate oxidase in patients with refractory gout. Arthritis Rheum. 2007 Mar;56(3):1021-8.

2007 -- Pubmed # 17928310 -- Sundy JS, Hauswirth DW, Mervin-Blake S, Fernandez CA, Patch KB, Alexander KM, Allgood S, McNair PD, Levesque MC. Smoking is associated with an age-related decline in exhaled nitric oxide. Eur Respir J. 2007 Oct 10.

2007 -- Pubmed # 17531181 -- Sundy JS, Hershfield MS. Uricase and other novel agents for the management of patients with treatment-failure gout. Curr Rheumatol Rep. 2007 Jun;9(3):258-64.

2007 -- Pubmed # 17103228 -- Webb BT, van den Oord E, Akkari A, Wilton S, Ly T, Duff R, Barnes KC, Carlsen K, Gerritsen J, Lenney W, Silverman M, Sly P, Sundy J, Tsanakas J, von Berg A, Whyte M, Blumenthal M, Vestbo J, Middleton L, Helms PJ, Anderson WH, Pillai SG. Quantitative linkage genome scan for atopy in a large collection of Caucasian families. Hum Genet. 2007 Mar;121(1):83-92.

2006 -- Pubmed # 16356199 -- Ganson NJ, Kelly SJ, Scarlett E, Sundy JS, Hershfield MS. Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene glycol) (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase. Arthritis Res Ther. 2006;8(1):R12.

2006 -- Pubmed # 16391567 -- Pillai SG, Chiano MN, White NJ, Speer M, Barnes KC, Carlsen K, Gerritsen J, Helms P, Lenney W, Silverman M, Sly P, Sundy J, Tsanakas J, von Berg A, Whyte M, Varsani S, Skelding P, Hauser M, Vance J, Pericak-Vance M, Burns DK, Middleton LT, Brewster SR, Anderson WH, Riley JH. A genome-wide search for linkage to asthma phenotypes in the genetics of asthma international network families: evidence for a major susceptibility locus on chromosome 2p. Eur J Hum Genet. 2006 Mar;14(3):307-16.

2005 -- Pubmed # 15866765 -- Schiffman SS, Studwell CE, Landerman LR, Berman K, Sundy JS. Symptomatic effects of exposure to diluted air sampled from a swine confinement atmosphere on healthy human subjects. Environ Health Perspect. 2005 May;113(5):567-76.

2004 -- Pubmed # 15349034 -- Hauswirth DW, Sundy JS. Bioaerosols and innate immune responses in airway diseases. Curr Opin Allergy Clin Immunol. 2004 Oct;4(5):361-6.

2003 -- Pubmed # 12674744 -- McCrory DC, Williams JW, Dolor RJ, Gray RN, Kolimaga JT, Reed S, Sundy J, Witsell DL. Management of allergic rhinitis in the working-age population. Evid Rep Technol Assess (Summ). 2003 Jan;(67):1-4.

2001 -- American Lung Association Asthma Clinical Research Centers (including JS Sundy). 2001. The safety of inactivated influenza vaccine in adults and children with asthma. N Engl J Med 345(21): 1529-36.